I'd say both of those definitely fit.
Your first example works for sure -- conflict is coming from the fact he was forced to finish working, but he hasn't been able to come to terms (get closure) on that. Hasn't been able to move on.
Your second example might need to focus more on the "closing down" part of it -- like the character is trying to end the estrangement. It does sound like you're bringing in the Counterpoint (Denial) -- the family member rejecting his efforts -- which is cool.
Closure or its lack could definitely result in depression and drinking, but I don't think the stop in "trying to stop depression by drinking" really fits Closure. The character isn't actually trying put an end to it, just trying to escape. However, there could be any number of Closure-related issues behind this. (e.g. they know they need to get divorced but afraid to pull the trigger and end the marriage)