Sure! The biggest thing bothering me though is whether Luke's a Do-er (Situation) or Be-er (Mind) regarding his personal issues. So far the only thing I found to go on in terms of how he actually acts re: his personal issues is his stealing the car, but that could be either (taking the car is Do-ing, but acting out could be Be-ing).
I agree with @Audz's logic about his destiny being something external -- except part of me thinks that (in this story) his personal issues are about his brother and being "frozen". Those issues are the ones that would be there without Boone's influence, whereas all the Situation & Future stuff seems to come with Boone's influence. Yet, he really, does have this terrible destiny he has to deal with, so I don't know, it's tough.
I wonder, do you see him more as having a hole in his heart (needing to start something) or a chip on his shoulder (needing to stop)?
Anyway, if we could try both (italics denote where I'm less sure)
Change, Start, Be-er, Linear, Decision, Optionlock, Success, Good; OS: Physics, Obtaining, Approach, Consider
This gives MC: Mind, Subconscious, Closure, Consider
And IC: Situation, Future, Openness, Conscience
OS Signposts: Learning -> Understanding -> Doing -> Obtaining
MC Signposts: Memories -> Preconscious (Impulsive Rsp) -> Conscious -> Subconscious
Change, Stop, Do-er, Linear, Decision, Optionlock, Success, Good; OS: Physics, Obtaining, Approach, Consider
This gives MC: Situation, Future, Openness, Consider
And IC: Mind, Subconscious, Closure, Control
OS Signposts: Doing -> Obtaining -> Learning -> Understanding
MC Signposts: Past -> Present -> Progress -> Future
You could play around with the Driver or Judgment to see if it gives you a different signpost order you like. I noticed that with Action Driver the OS Signposts were actually the same regardless of Do-er/Be-er, they were Learning -> Doing -> Obtaining -> Understanding.
Also, Symptom/Response are either Logic/Feeling (Do-er) or Feeling/Logic (Be-er). I could see Feeling having something to do with the NG's wyrds and especially Luke's, since it seemed kind of an emotional exploration, and Feeling can also represent instincts. Logic might be asking why, looking for cause/effect and trying to explain stuff, trying to make sense or thinking something doesn't make sense, etc. This pair feels right for your story, but hard to tell which is Symptom vs. Response.