Oh, indeed, “lots of people have lost jobs,” @SharkCat! But if times are hard (which they always are, for some people) and any of those employees have sick or malnourished children, the stakes of losing their jobs just rose appreciably (e.g., look at Bob Cratchit in A Christmas Carol, and many other desperate-times stories across the ages).
Also, an impact on relatives (siblings, parents, children, even aunts, uncles and cousins) can be quite enough to make the stakes matter to most audiences:
If I’m the sister, aunt, or any “only living relative” of the Antagonist, and I learn that my old-age financial support might be usurped by another “half” of that Antagonist, I too would strongly resist the two of them getting back together. Many a dramatic mystery has been based on such.
And see, I just suggested a mashup genre to throw in: A sci-fi mystery, that involves the MC trying to learn about his forgotten-by-him past as “a whole.” So he’s driven to learn about this past because some strangers keep trying to harm him.
And why? After several narrow escapes and investigations, he learns that these people fear how his returning to “wholeness” might cut off their financial security.
So I haven’t added any more than two to four characters, but this still does give us an Overall Story — “Battling Over Antag’s Wealth” — that involves all these characters in dramatic ways.
Finally, remember that every great story has a bit of “game” or “contest” to it.
So no matter what your contest/game/story is purportedly about (Obtaining, Understanding, The Past, or any of the other Dramatica Concerns), you’re setting up that one of the major obstacles preventing any character from winning this contest is the alienation and estrangement between the Antagonist and the Main Character.
And that Non-Acceptance could very well be the Problem lurking beneath and muddying up all the other efforts to Obtain, Understand, Play a Role, explore The Past, etc. (I’m essentially affirming your idea that the Problem is something like Non-Acceptance.)
Along with that, in my speculative version of your storyform, I set the MC as a Be-er (he’s “avoiding the world”), and the Story Goal as “Conceiving an Idea” (in a world where personalities and bodies can be split into two, but most people can’t imagine such, there will be a huge need for the ability to conceive such an idea).
Again, I’m speculating wildly based on your abstract references. But I’m just trying to inspire you to spend less time in Dramatica frustration and instead brainstorm more possiblities!