Have you seen Zootopia? Ask yourself how they do it.
Don’t forget the storyform is a holistic thing. If you started writing from a storyform with OS in Mind, and the source of the problem somehow “shifted” into Physics, it would be because you, the Author, shifted it. Subconsciously, maybe, but it would still be you. So, you’d probably find that the rest of the story shifted appropriately too and you were still following a valid storyform, just not the one you thought you were. (@MWollaeger has some anecdotes on this I think)
I feel like you keep coming up with reasons not to write this story. I don’t think anyone ever feels confident in their storyform when they start a work.
I think you have to pick some things to let go and just trust in the process. For me, that’s the message – I pick a storyform based on the idea for characters and plot that I see in my head, and don’t give a crap what the message actually is because I know that if there is a storyform, there’ll be a message, and that it will have come from the same place deep inside me that the ideas do. For you, I think you care about the exact argument you want to convey, so the same process likely won’t work – but you still have to let go of something. That might include your worries that the OS Domain will shift on you.
A key part of Dramatica is that we all recognize a complete story and its narrative argument subconsciously. There’s no point in using the theory if you don’t believe that. And if you believe that, you also have to believe that the same subconscious appreciation will help you tell your story, given the alignment that comes from working with a storyform and thinking about four throughlines.