In my experience it’s more important how you handle the storyform than the items you chose.
I’ve written psych-thrillers with Psychology OS Domain, but also with Universe OS Domain or Activities OS Domain…
It’s some sort of a tug-of-war between finding the right storyform and telling it right. In the end (and after several drafts) you’ll find the right form and the right telling.
Sigh! Nothing however saves us writers from doing several drafts!