It all depends on whether or not you think it makes your story better.
Even if you don't put it into context of the Issue above (like Unproven in terms of Wisdom - which, @Gernot, that is a great list!), the Audience will be able to make the connection themselves and be able to understand the message of your argument.
It's the old thing about whether or not you need to specifically encode the Problem in context of the Issue in context of the Concern in context of the Genre and whether or not these can be four completely separate things, or do they all have to connect.
The storyform makes all the connections for you--by virtue of the way the model was constructed. The idea that your story's Problem is Unproven and the Issue Wisdom - the Audience will naturally make that connection, even if your storytelling is vastly different and doesn't mix together well at all.
That's why theoretically you could have a Relationship Story Throughline between a MC and a character who is not the Influence Character, because it is the storyform that reigns supreme, not the story.
In short, you really don't need to worry about it to that amount of detail, let the storyform make the connections for you and just follow your intuition on what sounds fun to write.