I'm not sure I would put that way exactly. I don't think Dramatica technically requires consistency, because the storyform stands as its own unit. But from a storytelling perspective, I would think you would want some kind of consistency to make the character seem "real".
What would make sense to me is to have the character start from where he/she ended in the last story (assuming you are doing it sequentially), as in the Mrs. Maisel example. She doesn't feel inconsistent--she seems like her arc is continuing or going to the next phase.
I think it might be more useful to look at the whole story you're trying to tell. Part of the difficult thing to wrap your mind around with Dramatica is that characters are not "individuals" -- they only make sense in the context of the rest of the storyform. This, paradoxically, is what makes them seem real.
So yes, if you decide in book three that your OS Story must be in Universe (Situation), then in order for that story to feel complete, your MC will have to be either in Psychology or Physics.
It sounds like you're thinking of changing your OS Domain for each book in the series? I think this would be the thing that might makes the series feel inconsistent.